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doi: 10.1016/j.atherosclerosis.2018.07.014 [DOI] [PubMed] [Google Scholar] 132

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Over the past few decades, bone regeneration research has discovered that certain peptides might be able to play a role in speeding up the bone healing response [2]

Most patients experience no adverse effects, and when present, theyre typically mild and transient including temporary digestive changes as the gut adjusts, minor nausea (usually resolving within days), or altered bowel patterns during initial therapy

Another pathway in inhibition of TGF--mediated EMT by curcumin is that this plant derived-natural compound suppresses Smad2 phosphorylation, its nuclear translocation and interaction with promoter of Snail ( Fibrosis The endothelial-to-mesenchymal transition (EndMT) is a process in which endothelial cells lose their adhesion and polarity, and obtain mesenchymal phenotype, leading to enhanced cell migration and collagen secretion (Maddaluno et al., 2013)

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