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Mast cells are important for mediating inflammatory responses, which are deemed crucial during the initial phases of wound healing

Ultimately, this leads to mitochondrial damage and reduced biogenesis [15, 252, 253]

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It is now known that the LTC 4 transporter is the MR1P1/ABCC1 transporter ( K m 3 M) (Cole and Deeley, 2006, Nies and Keppler, 2007)
It has been suggested that reperfusion increases reactive oxygen species (ROS) production which can have further deleterious consequences
