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DSIP interacts with endogenous receptor systems and has been investigated for its influence on the hypothalamicpituitaryadrenal axis, positioning it as a signaling pathway modulator in stress-response and neuroendocrine research models [1]

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Importantly, diselenide linkages are dual-responsive, as they are susceptible not only to GSH reduction but also to oxidation by reactive oxygen species (ROS), such as hydrogen peroxide [59]