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[DOI] [PubMed] [Google Scholar] 102.Jotova I., Wang C., Tabib A., Dimitrov O., Bachrach U

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Secondary outcomes included biochemical redox markers such as blood GSH, cerebrospinal fluid (CSF) GSH, GSSG, and GSH/GSSG ratio and imaging-based functional outcomes, particularly DAT binding assessed by DaTscan SPECT

They concluded our observations strongly implicate mitochondrial dysfunction as the immediate cause of CFS symptoms (see Figure from [21])

Ddit3 , Bgn , Tmem150a , Sqstm1 , Hist1h2bc , Ccnd2 , Mxd4 , Ypel3 , Kdm5b , Mxra8 , and Grina , which were previously identified and preliminarily validated by single-cell sequencing, all exhibit increased expression with the replicative senescence of MEF cells and can serve as potential aging biomarkers for further investigation

doi: 10.1038/nature10361 [DOI] [PMC free article] [PubMed] [Google Scholar] 194.Pndy-Szekeres G, Munk C, Tsonkov TM, Mordalski S, Harpse K, Hauser AS, Bojarski AJ, Gloriam DE