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Abstract Blood clots are pivotal for haemostasis and regeneration 1 , but they are mechanically weak and form slowly 2 , posing risks for life-threatening haemorrhage and limiting broader applications 3,4,5

doi: 10.2147/CLEP.S99507

In males, early testosterone depletion has been identified as a risk factor for early-onset AD, with lower testosterone levels frequently linked to cognitive impairment [180]

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3.3 Metabolic fingerprinting analysis Metabolic fingerprinting is an untargeted metabolomics approach based on chromatographic profiles and MS peaks information that might correlate to chemical compounds through annotation

For kidney and heart tissue evaluation, a practicing renal/cardiovascular pathologist blind to the animals conditions/treatments performed light microscopic evaluated of H&E FFPE tissue from the sampled kidneys and hearts