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[DOI] [PubMed] [Google Scholar] 89.Deng L, Blanco FJ, Stevens H, Lu R, Caudrillier A, McBride M, McClure JD, Grant J, Thomas M, Frid M, et al
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In an animal study using 5-dihydrotestosterone + insulin treatment to simulate a miscarriage model in PCOS patients, NAC supplementation improved fetal survival rates in model mice by protecting mitochondrial function, restoring the balance of SOD1 and the Keap1/Nrf2 antioxidant response, reducing excessive ROS production, and mitigating placental formation defects [57]
Paik YH, Kim JK, Lee JI, et al
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This approach could reduce unwanted side effects and enhance therapeutic efficacy (151, 152)
