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In this review, we explored the interplay between oxidative PTMs, neoepitopes, and T1D, highlighting oxidative stress as a pivotal factor in immune system dysfunction, beta-cell vulnerability, and disease onset

doi: 10.1097/01.NAJ.0000731640.35662.2c

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Additionally, glutathione, an essential tripeptide antioxidant, is vital for GPX4's function in neutralizing hydrogen peroxide [13,14,15]

Therapeutic potential of SIRT1 activators in MASLD Previous studies have shown that SIRT1 plays a central regulatory role in multiple pathological processes of MASLD, including lipid metabolism disorders, insulin resistance, immune activation, oxidative stress, and gutliver barrier dysfunction