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Barzegar S, Rezvani MR, Safa M, Amani A, Abbaspour A, Pourfathollah A, et al

Xanthine oxidase inhibitor (XOI) therapy, particularly by use of allopurinol and febuxostat, is the primary approach used to treat hyperuricemia and thereby lower body urate stores [18]

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It has become apparent that an oxidized state favors maturation of viral hemagglutinin (HA) in the endoplasmic reticulum via a protein disulfide isomerase (PDI)-mediated mechanism

doi: 10.1038/tpj.2012.40