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Disrupted melanin synthesis pathway Melanin production depends on a chain of enzymatic reactions, starting with tyrosine, activated by the enzyme tyrosinase, and proceeding through several steps to produce eumelanin (brown-black pigment) or pheomelanin (red-yellow pigment)

Strong genetic predisposition to cancer, especially aggressive or early-onset cancers, elevates baseline risk

7 Loss of Ndufs2 in adipocytes leads to reduced complex I and III activity in gWAT, related to Fig

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With consistent dosing of cuprizone for 5 weeks, body weights were significantly affected in C57BL/6NTac versus C57BL/6J mice

Hydrogen sulfide SIBO is a newer category, typically associated with foul gas, sulfur odor, and a mix of symptoms