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However, CagriBB has equivalent potency to Cagri, in CRE-reporter assays in mammalian cells expressing AMY 3 Rs (Supplementary Table 4), suggesting there is negligible impact of this rotamer difference

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Gender-specific considerations While semaglutide works through the same mechanism in all bodies, there are practical differences in how men and women tend to respond and what considerations apply to each group

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