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Nrf2 then translocates into the nucleus and binds to antioxidant response elements in the promoter region of several antioxidant genes, such as heme-oxygenase-1 and NADPH-quinone-oxidoreductase-1

Dysregulation or genetic variations in GST genes can lead to altered enzyme activity, which may contribute to the development or progression of several diseases, including cancer, neurodegenerative disorders, cardiovascular diseases, and inflammatory conditions (an exhaustive list of diseases due to GST is given in databases like BRENDA ( DisGeNet ( and PHAROS ( (retrieved 23 September 2024)

Medical applications of phytoestrogens from the Thai herb Pueraria mirifica, PubMed

[PubMed] [Google Scholar] 2.Acetylcysteine: a drug with an interesting past and a fascinating future