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LeFort KR, Rungratanawanich W, Song B-J, LeFort KarliLeFort KR, Song bjsong B-J (2024) Contributing roles of mitochondrial dysfunction and hepatocyte apoptosis in liver diseases through oxidative stress, post-translational modifications, inflammation, and intestinal barrier dysfunction

Clinically, a meta-analysis of 14 randomized controlled trials ( n = 1,154) found that probioticTCM combinations were superior to 5-ASA monotherapy, probiotic monotherapy, or TCM monotherapy in inducing clinical remission, reducing relapse rates, and lowering adverse events (Hu et al., 2022)

GSTM3 is transcriptionally regulated by the NRF2/Keap1 signaling pathway and interacts with Cullin-associated and Neddylation-dissociated 1 (CAND1)

426,427 In a low pH environment, fusogenic peptides undergo pH-dependent conformational changes to form -helices, which insert into the endosomal membrane, causing instability and decomposition of the membrane structure

One aspect that has thus far received little attention is the antioxidant transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2)

The EF1B class is composed of TmGst13