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Description
While the NIH does not specify a tolerable upper intake level for vitamin B12, a study published in the JAMA Network Open found that high intakes of vitamin B12, such as from daily supplementation of 25 micrograms or higher, increased the risk of bone fracture [3] [4]

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Human liver nicotinamide N-methyltransferase
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Vitamin B12 Deficiency in Dogs Without enough vitamin B12, many of a dogs enzymatic and metabolic processes cant proceed normally, which results in clinical signs like: Poor growth in young animals Anemia (low red blood cell counts) Neurologic dysfunction Importantly, these signs are also often seen with the very health problems that lead to vitamin B12 deficiency
