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Always only fractions with the highest activity (+5) were selected for the next purification step

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Aside from a reduction in beneficial gliotransmission, the gut microenvironment can also shift EGCs towards a phenotype that releases specific gliomediators, such as nitric oxide (NO) [258]

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Over days and weeks, these fluctuations stress the peptide structure and can reduce potency faster than the BUD anticipates

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