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wound healing, where short-term SASP signaling recruits immune cells for tissue repair

Biochem Mol Biol Educ (2004) 32(5):291304

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Administration of CB-1158 (a small molecule inhibitor of arginase) can slow tumor growth rates, block myeloid cell-mediated suppression of T-cell proliferation, and increase the number of tumor-infiltrating CD8 + T cells and NK cells in mouse models of multiple tumors

However, neither POD nor RES affected the mRNA levels of GPR41 and GPR43 in liver (Figures 4C,D)