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1,5 An increased prevalence of nuclear cataracts has been associated in recent studies with other modifiable factors, especially smoking and marked obesity.6 A study of 1,808 women found that a healthy diet was the strongest modifiable predictor of low prevalence of nuclear cataract among numerous risk factors. 7 Patients with diabetes tend to develop precocious metabolic cataract, typically posterior subcapsular cataract (PSC) or cortical cataract

Crosstalk between autophagy and ferroptosis and its putative role in ischemic stroke

In this study, we have attempted to explain the mechanism of EA-associated bleeding by investigating its potential effect on the coagulation process

Similar results were obtained with mRNA expression of MMP-2 ( P =0.01), stromal-derived factor-1 (SDF-1) ( P =0.01), tumor growth factor (TGF)- ( P =0.001) and poly-(ADP-ribose) polymerase (PARP) that occurs in response to DNA damage ( P =0.001) (Figure 5b)

Clarifying whether autophagy acts protectively or destructively in the context of CIO is crucial for developing targeted interventions

Based on these findings, the authors concluded that dopaminergic neuron integrity was preserved, unlike in Parkinsons Disease