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[DOI] [PubMed] [Google Scholar] 26.M, Ingersoll RT, Lykkesfeldt J, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 416

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Matching with these findings, bulk transcriptomic profiling of cerebellar tissues harvested from 6-month-old mice revealed that differentially downregulated genes were highly involved in glycolysis, adipogenesis (i.e., lipid anabolism), and myogenesis (i.e., protein anabolism) (Supplementary Fig

-Sitosterol has been reported to inhibit a variety of cyclin-CDK complexes, upregulate the cell cycle inhibitor p27, and cause cells to arrest in the G1 phase, among others (86, 87)

Neumann B, Baror R, Zhao C et al (2019) Metformin restores CNS remyelination capacity by rejuvenating aged stem cells
