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These iron levels were not associated with increased ferritin, which sequesters iron in a biologically inert form, thus suggesting the accumulation of potentially harmful free iron (37)

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Our findings are supported by unaltered inflammatory parameters and intestinal morphology

It has been demonstrated that endonuclease inhibition decreases cell lethality (69), suggesting that DNA fragmentation has a permissive role in APAP liver toxicity

Furthermore, 1,2-DCP is a synthetic chlorinated solvent and is obtained as a by-product of the production of epichlorohydrin, which is used as a major chemical building block