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The HPV16 E7 oncoprotein directly suppresses the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling pathway, significantly reducing the expression of genes that encode type I interferon and pro-inflammatory proteins, hence facilitating immune evasion in several HPV-related tumors in murine models (Luo et al., 2020)

doi: 10.1038/s41467-017-01366-x

doi: 10.1001/jama.2021.21187 174

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2017 Jul Banner Image Designed by Freepik About the Author Katie is a qualified Naturopath (BNatMed) and freelance writer from New Zealand

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