glp 1 and cold intolerance Why do GLP-1s do this? π₯Άπ₯, If you started a GLP-1 suddenly feel for no reasonβ¦ youβre not imagining it. Welcome to the chills. βοΈ, Some say itβs from weight loss (nope, not yet), or your Is Cold Sensitivity a Side
Description
The findings of a new study suggest that an apparent association between GLP-1 medications and thyroid cancer may be due to more intensive patient screening, and not a side effect of the drugs themselves.
100% of participants confirmed DermaReverse was gentle enough for daily use
adults that examines Americans' evolving attitudes and behaviors toward GLP-1 medications
Others * Long-term metformin use * Proton pump inhibitors (reduce acid absorption) Pathophysiology * Impaired DNA synthesis megaloblastic anemia * Accumulation of methylmalonic acid nerve damage Clinical features Hematological * Fatigue, pallor * Shortness of breath * Megaloblastic anemia Neurological (key distinguishing feature) * Peripheral neuropathy (tingling, numbness) * Loss of vibration and position sense * Ataxia (unsteady gait) * Cognitive changes Severe untreated cases irreversible nerve damage Others * Glossitis (smooth, beefy red tongue) * Mild jaundice Investigations * Serum vitamin B12 * CBC macrocytic anemia ( MCV) * Blood film hypersegmented neutrophils * methylmalonic acid (specific for B12 deficiency) * homocysteine Differentiate from folate deficiency * Both megaloblastic anemia * Only B12 neurological symptoms Management Replacement therapy * Hydroxocobalamin (preferred IM) * Frequent doses initially, then maintenance * Oral B12 if mild and absorption intact Important rule Never give folate alone if B12 deficiency is possible may worsen neurological damage Prevention * Adequate diet (meat, eggs, dairy) * Supplementation in vegans * Monitor high-risk patients (elderly, post-surgery)
Whats included
Supports Thyroid Function | Hormonal Regulation | Cellular Protection
