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Description
Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells
When the intracellular concentration of calcium rises this transport process is less favorable since the calcium gradient is reduced

Promotes cognitive function

doi: 10.3390/antiox11040660 175 KotterM

On the other hand, in the amyloidogenic pathway, APP at the N-terminal part of the A domain is cleaved by -site APP cleaving enzyme 1 (formerly known as -secretase) (BACE-1), resulting in release of extracellular soluble fragments of sAPP and a membrane bound C99 or -CTF [129, 130]

Apple, A
