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Okayama Y, Matsumoto H, Odajima H et al (2020) Roles of omalizumab in various allergic diseases

Excitotoxicity is a condition produced by excessive glutaminergic stimulation that can lead to abnormally high extracellular glutamate levels and causes spikes in intracellular calcium levels and triggers neurotoxic signaling cascades (Ribeiro et al., 2017)
2014;9:e88532

Plaque psoriasis is highly prevalent, accounting for 90% of psoriasis patients
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This process involves the accumulation of glycosaminoglycans within the valve layer, leading to structural weakening and leaflet redundancy