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Cholesterol overloaded macrophages exhibited an increased Toll-like receptor 4 (TLR-4) signaling mediated immune response as well as elevated expression levels of IL-1, emphasizing a potential role of NLRP3 inflammasome activation in pulmonary macrophages (Robert et al., 2016)
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[DOI] [PubMed] [Google Scholar] 64.Gupta J., Gupta K., Jaiswal R., Vashisht H
They found that levels were significantly decreased in these patients, as compared to age-matched individuals without depression

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes