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PE-22-28 also appears to have seizure-protective properties rather than seizure-promoting effects, which addresses one of the theoretical concerns with TrkB agonism

[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Truffault V., Fry S.C., Stevens R.G., Gautier H

This constitutes a potential limitation in terms of generalizability, as sex-dependent pathological features in PTSD remain incompletely characterized
Kaji R, Kodama M, Imamura A, Hashida T, Kohara N, Ishizu M, Inui K, Kimura J

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