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Quantification of BBB dysfunction was calculated as described previously 70,72

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Med 16 , 3854 (2019)
However, upon exposure to powerful pro-oxidant stimuli such as dapsone or primaquine, acute extravascular and then intravascular hemolysis can occur leading to the release of heme and free iron into the local intravascular environment 57
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86 Putative causes include translocation of bacterial products across the GI tract, persistent HIV and co-infection with other pathogens, such as CMV and HCV
