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The fact that this MIC far exceeds the clinical breakpoint by several-fold to tens of folds strongly suggests that the bacterium likely produces drug-inactivating enzymes, such as aminoglycoside-modifying enzymes, which efficiently destroy antibiotic molecules, leading to high-level resistance

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Similarly, its not meant for large-volume IV infusion

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Mimo obiecujcych wynikw, naley pamita, e wikszo bada przeprowadzono na modelach zwierzcych, a kontrolowanych bada klinicznych u ludzi jest wci niewiele