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Common complications of facial injection include infections, bleeding, foreign body reaction, erythema, swelling, itching, bruising, induration, depigmentation, lumpiness, ulceration, and vascular complication, 3,16,17 among which RGM infection is rare

MATERIALS AND METHODS Animals Swiss male albino mice 25-30 g of body weight were used

Ethical approval This study received ethical approval from the Ethics Committee of the Eye, Ear, Nose, and Throat (Eye & ENT) Hospital of Fudan University (approval number: 81470613, date of approval: 2020-06-01)

Both the ADH1B*2 and ADH1B*3 encoded subunits harbor amino acid substitutions that affect the binding of the NAD + cofactor