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Entity anchored ICD coding

Elevated levels of both enantiomers of 2HG in human body fluids have been strongly associated with mutations in SLC 25A1, a member of the mitochondrial carrier protein family ( SLC 25), which comprises 53 human isoforms ( SLC 25A1- SLC 25A53) ( SLC 25A1 encodes a citrate carrier protein located in the inner mitochondrial membrane, consisting of 311 amino acids with a molecular mass of 34.013 kDa, and is mapped to chromosome 22q11.2

This represents a niche application distinct from the systemic effects sought with nasal or injectable administration

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