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In conclusion, Protandim did not (1) alter 5-km running time, (2) lower TBARS at rest (3) raise antioxidant enzyme concentrations compared to placebo (with exception of SOD in those 35 years old) or, (4) affect quality of life compared to placebo

[ 2 ] Furthermore, low glutathione levels seem to play a rather critical role when it comes to premature aging , as well as chronic age-related conditions such as macular degeneration [ 2 ], which is precisely one of the main tenets of The Glutathione Revolution book