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Description

IGF1 indirectly increases DNA repair by 50% through increasing the p53 dependence in the p21, while inhibition IGF1R by siRNA in human prostate cancer cells enhances the sensitivity of ionizing radiation to SSBs and DSBs (Clark et al., 2005)

This leads to low immunity and an increase of sickness during those seasons

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Persistent side effects beyond 2 weeks after a dose increase Transient nausea, mild constipation, and decreased appetite are expected and normal during the 1 to 2 weeks after each dose increase

That designation effectively bars licensed compounding pharmacies from making them, citing immunogenicity risks, impurities in the raw ingredient, difficulty verifying exactly whats actually in the drug (the FDA calls this API characterization, essentially confirming the active ingredient is what it claims to be), and, in many cases, a lack of human safety data (more on FDA)