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Efficacy of Glucagon-like Peptide-1 Receptor Agonists in Overweight/Obese and/or T2DM Adolescents: A Meta-Analysis Based on Randomized Controlled Trials

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To conduct the study, the authors selected randomized placebo-controlled trials from PubMed, Embase, Web of Science, Scopus, and the Cochrane Central Register of Controlled Trials through August 2025

Data availability The pseudonymized patient-level data collected from regional registers are not allowed to share publicly due to confidentiality reasons

Among the 12% of adults who have ever taken GLP-1 drugs, most report taking them, at least in part, to treat a chronic condition like diabetes or heart disease, with fewer saying they took them only to lose weight

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