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Under high copper concentrations, free intracellular copper ions accumulate and inhibit enzyme function by oxidizing cysteines in iron-sulphur cluster proteins or react chemically with hydrogen peroxide to generate highly reactive hydroxyl radicals, thereby inducing cellular damage (12)

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[DOI] [PubMed] [Google Scholar] 95.Kayser R.R., Haney M., Raskin M., Arout C., Simpson H.B
