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(2024) recently discovered that guanidine, produced by Bacteroides vulgatus, although a microbial metabolite, has a mechanism of action that is completely different from that of TMAO

Retired National Football League (NFL) players, for example, have a threefold increased risk of developing depression after retirement if they had received multiple concussions throughout their career

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A shortcoming, however, is that current literature on the relevance of the gutbone axis in orthopedic diseases remains insufficient and lacks a more comprehensive synthesis on how to combine the two or how to combine them with other organs