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transient impairment of glucose tolerance is possible, particularly in individuals with pre-existing insulin resistance Injection site reactions: Mild and typically localised Contraindications include active malignancy (GH-IGF-1 signalling can promote tumour growth), pituitary-dependent conditions, pregnancy, and active diabetic retinopathy

[DOI] [PubMed] [Google Scholar] 87.Shah Z.A., Nada S.E., Dore S

[DOI] [PMC free article] [PubMed] [Google Scholar] Lin Z, Fang D

A Pew Research Center survey from February 2026 found that 49% of U.S

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