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Also, mean ALP and LDH activity were lower in the intervention compared to the control group significantly ( p = 0.010 and p = 0.002, respectively

This product is registered as a food supplement with no approved therapeutic claims

Funding Statement This work was supported by Fundao para a Cincia e a TecnologiaFCT to IBIMED (UIDP/04501/2020 and UIDB/04501/2020) and LAQV/REQUIMTE (UIDB/50006/2020)

however, two cases studies suggest greater pain reduction with increased doses, longer duration, and more frequent treatments

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One of the physiological substrates of this transporter is acetylcholine, underlying a key role in the non-neuronal cholinergic system in both physiological and pathological conditions, as testified by the occurrence of a natural mutation of OCTN1 in inflammatory conditions such as Crohns Disease (Pochini et al., 2019)
