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Similarly, a larger, multi-center trial using Avmacol (Ou et al., 2024) showed mixed results, reporting no significant differences in caregiver ratings for ABC and SRS scores

doi: 10.1016/j.niox.2019.03.002

Besides, glutathione deficiency is one less problem to worry about

Dayanandan AP, Cho WJ, Kang H, Bello AB, Kim BJ, Arai Y, et al
Localization and role of NPC1L1 in cholesterol absorption in human intestine

One of these neurotoxic kynurenine metabolites is quinolinic acid, an agonist of the NMDA receptor
