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In contrast, renal cell carcinoma [151] or prostate cancer [152], HIF-1 tends to suppress ferroptosis via upregulation of lipid antioxidants such as SLC7A11 or FSP1

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Quintas-Cardama A, Tefferi A, Thomas D, Cortes J, Ravandi F, Faderl S, Garcia-Manero G, Borthakur G , Bell N, Byrne C, Kantarjian H, Verstovsek S

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5.2 Cellular crosstalk Intestinal epithelial cells (IECs) constitute a critical physical barrier that segregates the intestinal lumen, with its diverse contents, including digested nutrients, commensal microbiota, and potential pathogens, from the underlying mucosal immune system (164)

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