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Chapter 53: Molecular therapies for cystic fibrosis, in Kendig's Disorders of the Respiratory Tract in Children, 9th Edn , eds WilmottR

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Controlling the role of BPC 157 likely involves its particular interaction with the major systems involved in wound healing, such as the NO-system (counteracted harmful events, arising from either NO-blockade or NOS-substrate application) (Sikiric et al., 2014) and the prostaglandins system (i.e., large extent of the counteracted NSAIDs toxicity (Sikiric et al., 2013) as well as counteracted developing and already formed adjuvant arthritis in rats (Sikiric et al., 1997c))

Where available, PK/PD parameters, biomarker readouts, and safety-relevant findings were also captured