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[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Levin SG, Godukhin OV

Asiaticoside inhibits P2X purinoceptor 7 (P2RX7)-mediated TGF-/SMAD signaling by upregulating the expression of peroxisome proliferator-activated receptor gamma (PPARG), thereby inhibiting TNBC cell migration, invasion, and EMT [211]

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FOXO4-DRI interferes with this binding, reactivating p53s apoptotic function and selectively eliminating senescent cells (1)