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[PubMed] [Google Scholar] 26.Braverman ER, Bowirrat A, Damle UJ, Yeldandi S, Chen TJ, et al

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This provided sustained BA release through the cornea over 12 h [123]

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BPC-157 has been shown to upregulate VEGFR2 (vascular endothelial growth factor receptor 2) and promote angiogenesis through nitric oxide (NO) system modulation, as documented in research examining its effects on muscle and tendon healing

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However, adverse effects may limit the treatment potential, e.g., glitazones are associated with phenotypical weight gain [136] and obeticholic acid induced pruritus and elevated LDL-C [137], the latter a potential concern in patients already at risk for cardiovascular disease

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Pharmacological therapies and their clinical targets in irritable bowel syndrome with diarrhea

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doi: 10.1038/nature13034 38 LehmannMNikolicDSPiguetV

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