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However, apoptosis was undetectable when cells were treated with HCH, washed and then treated with BSO (Fig

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Oxidative stress affects numerous molecular pathways, including inhibition of the cystine/glutamate antiporter system, decreased expression of GPX4, disruption of iron homeostasis and lipid peroxidation, which is a major driver of ferroptosis activation (54)

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data not shown) or showed no significant difference (2, 5, V, 2)
