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Can metabolic plasticity be a cause for cancer
IGF-1/-2-neutralizing monoclonal antibodies inhibit various IGF signaling pathways at the same time but have a lower risk of hyperglycemia than IGF-1R/INSR tyrosine kinase inhibitors, as they do not affect insulin receptor-, which regulates glucose homeostasis [116]
RT-qPCR was performed in triplicate in a Rotor-Gene thermal cycler (Bio-Rad)
Recent studies have highlighted the complex relationship between iron deficiency and tumor biology
doi: 10.17179/excli2021-3596 [DOI] [PMC free article] [PubMed] [Google Scholar] 15
