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Model analysis Selection of parameters for estimation The methodology to select parameters for estimation involves first conducting local sensitivity analysis (LSA) to obtain a set of important parameters, and then determining from this set of parameters which are identifiable, that is for which parameters a value can be identified from the data, taking into account the model structure

doi: 10.3390/life10110271 196 NomuraE.OhtaY.TadokoroK.ShangJ.FengT.LiuX.et al

CONCLUSION Although MEM shows an adequate profile in preclinical AD models, clinical data have not reported satisfactory results for curing the disease [127, 128]

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