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Oxidative Medicine and Cellular Longevity, 2011 , 194586
Conversely, low levels of HIF-1 downregulate downstream target genes such as phosphoinositide-dependent protein kinase-1 (PDK1) and GLUT1, thereby regulating the glycolytic pathway and intracellular adenosine triphosphate (ATP) supply (35)
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One component of this cascade might involve nitric oxide production within the VTA, suggesting a complex interaction between Oxytocin, dopamine, and nitric oxide in this context
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