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There are numerous considerations for selecting these two compounds in the list, including factors such as pH, stability, osmolality, and lipophilicity

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General Psychiatry 35 (4), e100782

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Moreover, SCFAs such as butyrate and propionate enhance regulatory T cell (Treg) differentiation by activating G-protein-coupled receptors (GPR41, GPR43, and GPR109A) and inhibiting histone deacetylases (HDACs), promoting the expansion of Foxp3 + Tregs [59]

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