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However, genetic studies cannot provide the same fine-tuning and evaluation of dose-dependency and dosage scheduling that is possible with pharmacological agents

Schroeder, Nature Chemical Biology

Cudalbu C et al (2021) Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

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However, no positive effect on disease activity was observed, and there was no alteration in the examined immune biomarkers in the peripheral blood

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