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Hepatology 66 , 16011615 (2017)

10.1007/s00592-018-1217-9 117 KuthatiY.BusaP.Goutham DavuluriV

Unlike regular SELEX, which can take up to 1520 rounds, CE-SELEX can isolate high-affinity aptamers in as little as 1-4 rounds, significantly reducing development time and expenses (Zhuo et al., 2017)

[DOI] [PubMed] [Google Scholar] Wang B

However, there have been significant advancements in recognizing the importance of these compounds in mammals and their involvement in the mediation of inflammation, nociception, and cell proliferation, as well as in immuno- and tissue modulation, coagulation processes, hormone regulation, and skin barrier formation

Chronically taking 7.5 mg when you think you are taking 5 mg means you are on a different pharmacological trajectory than intended