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This enzymatic reaction consumes both nicotinamide and SAM, leading to depletion of NAD+ storesa critical coenzyme required for cellular energy production, DNA repair, and metabolic regulation

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Siasos G, Tsigkou V, Kosmopoulos M, Theodosiadis D, Simantiris S, Tagkou NM, Tsimpiktsioglou A, Stampouloglou PK, Oikonomou E, Mourouzis K, et al

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Conditions like insulin resistance, thyroid dysfunction, and hormonal imbalance the very issues Meto's clinical programs address are well-established drivers of the symptoms (fatigue, poor recovery, body composition changes) that many people turn to peptides hoping to resolve
