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Description
J., Reddy, V., Henderson, S

Cell membrane permeabilization was achieved using 0.1% Triton X-100 in PBS for 10 min, followed by immunological blocking with 1% BSA in PBS for 60 min
The theory hypothesizes that aging is associated with structural impairment caused due to the accumulation of oxidative damage to crucial macromolecules (lipids, DNA, RNA, and proteins) brought about ROS and RNS (Liguori et al., 2018)

The role of mitochondria in cellular senescence

It helps neutralize free radicals and regulate melanin (skin pigment)
Recently, inflammasome activation of IL-1 and IL-18 has been implicated in atherogenesis (63,64)
