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Luo et al ., 2012 Plant Cell)
Mitochondrial dysfunction is characterized by various degrees of ultrastructural mitochondrial damage, abnormal morphologic changes, increased permeability of the outer and inner membranes, impaired mitochondrial -oxidation, respiratory chain activity reduction, ROS overproduction, ATP depletion, and oxidative stress-mediated deletions of mtDNA inducing apoptosis (Ramanathan et al

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Biol Reprod 98:784794 Lee JJ, Chang-Chien GP, Lin S et al (2022) 5-lipoxygenase inhibition protects retinal pigment epithelium from sodium iodate-induced ferroptosis and prevents retinal degeneration

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In recent years, there has been growing interest in the potential benefits of glutathione supplementation for individuals with lupus
